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Overview
cgc4386_cluster_4_2
Species:
Caenorhabditis elegans
Attribute of Microarray experiment:
WormBase ID:
cgc4386_cluster_4_2
Developmentally modulated gene cluster.
The expression profile of each of 4221 developmentally modulated genes that had a significant (P<0.001) increase or decrease in frequency at some point during the life cycle and that were called present at least once was normalized to have a mean value of zero and a variance of one, and the normalized profiles were clustered by means of a self-organizing map.
Algorithm:
self-organizing mapRemarks:
Type: Co-expression ClusterThe expression profile of each of 4221 developmentally modulated genes that had a significant (P<0.001) increase or decrease in frequency at some point during the life cycle and that were called present at least once was normalized to have a mean value of zero and a variance of one, and the normalized profiles were clustered by means of a self-organizing map.
Associations
Anatomy Terms:
Life Stages:
GO terms:
Processes:
| Processes | Definition |
|---|---|
| Development | Development is the process of temporal and spatial control of gene expression that gives rise to a fully functional adult form of the organism. Studies of development in C. elegans have traced every cell from birth to final differentiated state in the developing nematode. These studies have elucidated cellular, genetic, and molecular mechanisms that control the division, growth, differentiation and morphogenesis of cells giving rise to tissues and organs in the nematode body. While most terminally differentiated cells can be traced by lineage back to a founder cell, there still remains a few cells types in the nematode with stochastic identity, relying on signals from the environment for their final identity. |
References
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Journal article
1
1 reference found
Genomic analysis of gene expression in C. elegans.
Journal article
Science
2000
Until now, genome-wide transcriptional profiling has been limited to single-cell organisms. The nematode Caenorhabditis elegans is a well-characterized metazoan in which the expression of all genes can be monitored by oligonucleotide arrays. We used such arrays to quantitate the expression of C. elegans genes throughout the development of this organism. The results provide an estimate of the number of expressed genes in the nematode, reveal relations between gene function and gene expression that can guide analysis of uncharacterized worm genes, and demonstrate a shift in expression from evolutionarily conserved genes to worm-specific genes over the course of development.
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Regulation
No regulation data for cgc4386_cluster_4_2
Regulated by Gene:
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