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Species » C. elegans(Genome assembly: WBcel235)

Expression cluster » WBPaper00059253:resveratrol_downregulated

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  • Overview

    WBPaper00059253:resveratrol_downregulated

    Species:
    Caenorhabditis elegans
    WormBase ID:
    WBPaper00059253:resveratrol_downregulated
    Transcripts that showed significantly decreased expression among animals treated with 400mM sucrose, 500 mg per ml stearic acid and 500mg per ml resveratrol from L1 to L4 larva stage comparing to animals treated with only 400mM sucrose and 500 mg per ml stearic acid plates.

    Algorithm:

    CuffDiff, FDR <= 0.05, fold change >= 2.

    Remarks:

  • Regulation

    Regulated by Gene:
    Regulated by Treatment:
    Regulated by Molecule:
    resveratrol

  • References

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      • Journal article

      1

    1 reference found
    Effects of excess sugars and lipids on the growth and development of <i>Caenorhabditis elegans</i>.
    Journal article
    Genes Nutr
    2020

    Background: . Methods: Results: . Conclusion: High-sugar and high-lipid intake altered the expression of genes involved in biofilm synthesis, genes that catalyze the synthesis and degradation of endogenous substances, and genes involved in innate immunity, resulting in physiological damage. Furthermore, we explored the protective effect of resveratrol on high-sugar and high-lipid damage to nematodes. Resveratrol plays a role in repairing by participating in the metabolism of foreign substances and reducing cellular oxidative stress.

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  • Associations

    Anatomy Terms:
    Life Stages:
    Life Stages Definition
    L4 larva CeThe fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.
    GO terms:
    Processes: