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Resources » Process&Pathway

Dosage compensation

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  • Overview

    Dosage compensation

    Other name:
    Life stage:
    WormBase ID:
    WBbiopr:00000056
    A mechanism for regulating chromosome-wide gene expression based on the ratio of autosomes to sex chromosomes. In C. elegans, the hermaphrodite is XX with two X chromosomes while the male is X0 with only one X chromosome. Dosage compensation machinery in these nematodes reduces expression of genes on both X chromosomes in the hermaphrodite.
    Related processes:

    Specialization of:

    Sex detemination
    Development

    Historical gene: