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Resources » Paper

Crombie TA et al. (2023) Nucleic Acids Res "CaeNDR, the Caenorhabditis Natural Diversity Resource."

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  • Comments on Crombie TA et al. (2023) Nucleic Acids Res "CaeNDR, the Caenorhabditis Natural Diversity Resource." (0)

  • Overview

    PMID:
    37855690
    DOI:
    10.1093/nar/gkad887
    Status:
    Publication type:
    Journal_article
    WormBase ID:
    WBPaper00066113

    Crombie TA, McKeown R, Moya ND, Evans KS, Widmayer SJ, LaGrassa V, Roman N, Tursunova O, Zhang G, Gibson SB, Buchanan CM, Roberto NM, Vieira R, Tanny RE, & Andersen EC (2023). CaeNDR, the Caenorhabditis Natural Diversity Resource. Nucleic Acids Res. doi:10.1093/nar/gkad887

    Studies of model organisms have provided important insights into how natural genetic differences shape trait variation. These discoveries are driven by the growing availability of genomes and the expansive experimental toolkits afforded to researchers using these species. For example, Caenorhabditis elegans is increasingly being used to identify and measure the effects of natural genetic variants on traits using quantitative genetics. Since 2016, the C. elegans Natural Diversity Resource (CeNDR) has facilitated many of these studies by providing an archive of wild strains, genome-wide sequence and variant data for each strain, and a genome-wide association (GWA) mapping portal for the C. elegans community. Here, we present an updated platform, the Caenorhabditis Natural Diversity Resource (CaeNDR), that enables quantitative genetics and genomics studies across the three Caenorhabditis species: C. elegans, C. briggsae and C. tropicalis. The CaeNDR platform hosts several databases that are continually updated by the addition of new strains, whole-genome sequence data and annotated variants. Additionally, CaeNDR provides new interactive tools to explore natural variation and enable GWA mappings. All CaeNDR data and tools are accessible through a freely available web portal located at caendr.org.

    Authors: Crombie TA, McKeown R, Moya ND, Evans KS, Widmayer SJ, LaGrassa V, Roman N, Tursunova O, Zhang G, Gibson SB, Buchanan CM, Roberto NM, Vieira R, Tanny RE, Andersen EC


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