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PMID:
Status:
Publication type:
Journal_article
WormBase ID:
WBPaper00062413
Charlesworth AG, Nitschko V, Renaud MS, & Claycomb JM (2022). PIWI puts spermatogenesis in its place. Dev Cell, 57, 149-151. doi:10.1016/j.devcel.2022.01.001
In this issue of Developmental Cell, Cornes et al. show that piRNAs initiate transcriptional silencing of spermatogenesis genes in the C.elegans germline via an endogenous nuclear RNAi pathway. This silencing enables a timely transition from spermatogenesis to oogenesis during hermaphrodite development, thus promoting fertility.
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