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Comments on Kron M et al. (1995) FEBS Lett "An immunodominant antigen of Brugia malayi is an asparaginyl-tRNA synthetase." (0)
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PMID:
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Publication type:
Journal_article
WormBase ID:
WBPaper00056580
Kron M, Marquard K, Hartlein M, Price S, & Leberman R (1995). An immunodominant antigen of Brugia malayi is an asparaginyl-tRNA synthetase. FEBS Lett, 374, 122-4. doi:10.1016/0014-5793(95)01092-s
Lymphatic filariasis is caused by infection with the filarial nematodes Brugia malayi, Brugia timori, Wuchereria bancrofti and Onchocerca volvulus which collectively infect about 200 million persons throughout the world. Protein sequence homology analysis of a major nematode antigen suggested that it was a class II aminoacyl-tRNA synthetase. The overproduction, purification and verification that the major B. malayi antigen is an asparaginyl-tRNA synthetase is described.
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