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Resources » Paper

Svendsen JM et al. (2018) Dev Cell "piRNA Rules of Engagement."

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  • Overview

    PMID:
    29587140
    DOI:
    10.1016/j.devcel.2018.03.006
    Status:
    Publication type:
    Journal_article
    WormBase ID:
    WBPaper00053898

    Svendsen JM, & Montgomery TA (2018). piRNA Rules of Engagement. Dev Cell, 44, 657-658. doi:10.1016/j.devcel.2018.03.006

    piRNAs are known to silence transposable elements, but not all piRNAs match transposon sequences. Recent studies from Shen etal. (2018) and Zhang etal. (2018) identify rules for piRNA target recognition in Caenorhabditis elegans. Permissive pairing rules allow targeting of essentially all germline mRNAs, while protective mechanisms prevent silencing self-genes.


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