Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.
  • page settings
  • hide sidebar
  • show empty fields
  • layout
  • (too narrow)
  • open all
  • close all
Resources » Paper

Vrbanac A et al. (2017) Cell Host Microbe "An Elegan(t) Screen for Drug-Microbe Interactions."

  • History

  • Referenced

  • Tree Display

  • My Favorites

  • My Library

  • Comments on Vrbanac A et al. (2017) Cell Host Microbe "An Elegan(t) Screen for Drug-Microbe Interactions." (0)

  • Overview

    PMID:
    28494234
    DOI:
    10.1016/j.chom.2017.04.014
    Status:
    Publication type:
    Journal_article
    WormBase ID:
    WBPaper00051214

    Vrbanac A, Debelius JW, Jiang L, Morton JT, Dorrestein P, & Knight R (2017). An Elegan(t) Screen for Drug-Microbe Interactions. Cell Host Microbe, 21, 555-556. doi:10.1016/j.chom.2017.04.014

    Microbes affect drug responses, but mechanisms remain elusive. Two papers in Cell exploit C.elegans to infer anticancer drug mechanisms. Through high-throughput screens of drug-microbe-host interactions, Garcia-Gonzalez etal. (2017) and Scott etal. (2017) determine that bacterial metabolism underpins fluoropyrimidine cytotoxicity, providing a paradigm for unraveling bacterial mechanisms in drug metabolism.


    Tip: Seeing your name marked red? Please help us identify you.