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Resources » Paper

Gerhold AR et al. (2016) Dev Cell "Bigger Isn't Always Better: Cell Size and the Spindle Assembly Checkpoint."

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  • Overview

    PMID:
    26859348
    DOI:
    10.1016/j.devcel.2016.01.017
    Status:
    Publication type:
    Comment
    WormBase ID:
    WBPaper00050153

    Gerhold AR, Labbe JC, & Maddox PS (2016). Bigger Isn't Always Better: Cell Size and the Spindle Assembly Checkpoint. Dev Cell, 36, 244-6. doi:10.1016/j.devcel.2016.01.017

    Variation in the activity of the spindle assembly checkpoint has been observed in different cell types, yet the reason for this variability remains poorly understood. Reporting in Developmental Cell, Galli and Morgan (2016) show that checkpoint activity increases during development as cell size, and the cytoplasm-to-kinetochore ratio, decreases.


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