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PMID:
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Publication type:
Journal_article
WormBase ID:
WBPaper00049663
Tatar M, & Sedivy JM (2016). Mitochondria: Masters of Epigenetics. Cell, 165, 1052-1054. doi:10.1016/j.cell.2016.05.021
Accumulating evidence argues that aging exerts a profound influence on epigenetics, and vice versa. A pair of studies by Merkwirth etal. and Tian etal. now provide insights on how mitochondrial stress experienced by C.elegans larvae propagates a specific and persistent epigenetic response that protects adult cells and extends lifespan.
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