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Resources » Paper

Manning BD (2013) Cancer Cell "Adaptation to starvation: translating a matter of life or death."

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  • Overview

    PMID:
    23763997
    DOI:
    10.1016/j.ccr.2013.05.012
    Status:
    Publication type:
    Comment
    WormBase ID:
    WBPaper00044429

    Manning BD (2013). Adaptation to starvation: translating a matter of life or death. Cancer Cell, 23, 713-5. doi:10.1016/j.ccr.2013.05.012

    There is much interest in defining the nutrient dependencies of cancer cells and their mechanisms of adaptation to nutrient depletion. In a recent issue of Cell, Leprivier and colleagues demonstrate that eEF2K, which can inhibit translation elongation acutely during protein synthesis, is a critical switch in the survival versus death fate of starved cancer cells.


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