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Resources » Paper

Zaratiegui M et al. (2012) Nat Genet "The persistence of a silent memory."

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  • Overview

    PMID:
    22281766
    DOI:
    10.1038/ng.1088
    Status:
    Publication type:
    News, Comment
    WormBase ID:
    WBPaper00040702

    Zaratiegui M, & Martienssen R (2012). The persistence of a silent memory. Nat Genet, 44, 118-9. doi:10.1038/ng.1088

    One of the most striking properties of RNA interference (RNAi) in Caenorhabditis elegans is its persistence in offspring after the triggering double-stranded RNA (dsRNA) has disappeared. A new study reveals that a heterochromatic silencing mark is deposited around the targets of RNAi and is transmitted through generations. These results show that RNAi can induce stable and heritable chromatin modifications in animals.


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