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Resources » Paper

Ana Vinuela et al. (2010) Evolutionary Biology of Caenorhabditis and Other Nematodes "Transcriptional consequences of recombination in aging C. elegans"

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  • Comments on Ana Vinuela et al. (2010) Evolutionary Biology of Caenorhabditis and Other Nematodes "Transcriptional consequences of recombination in aging C. elegans" (0)

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    Publication type:
    Meeting_abstract
    WormBase ID:
    WBPaper00036692

    Ana Vinuela, L. Basten Snoek, Joost A.G. Riksen, & Jan E. Kammenga (2010). Transcriptional consequences of recombination in aging C. elegans presented in Evolutionary Biology of Caenorhabditis and Other Nematodes. Unpublished information; cite only with author permission.

    Recently, we explored genome-wide gene expression variation and regulatory loci (eQTL) in an N2 x CB4856 recombinant inbred population of developing and aging C.elegans worms (Viuela, et al., Genome Research, 2010). Here we present gene expression profiles of the two parental strains. We explored gene expression heritability and transgression as genetic parameters for the analysis of gene expression divergence in natural isolates. Moreover, we investigated the progression of those parameters with age. Preliminary results showed a strong influence of age in the transcriptional profile as well as a changed influence of the genotype in gene expression divergences in older worms. Research is ongoing to understand those results in a context of evolutionary forces affecting gene transcription divergences between two natural isolates.


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