- page settings
- showhide sidebar
- showhide empty fields
- layout
- (too narrow)
- open all
- close all
- Page Content
- Overview
- External Links
- History
- Referenced
- Tools
- Tree Display
- My WormBase
- My Favorites
- My Library
- Recent Activity
- Comments (0)
history logging is off
Tree Display
My Favorites
My Library
Comments on Gary Williams et al. (2006) European Worm Meeting "Curating Wormbase Gene Structures" (0)
Overview
Gary Williams, Paul Davis, Anthony Rogers, Philip Ozersky, John Spieth, Tamberlyn Bieri, & Darin Blasiar (2006). Curating Wormbase Gene Structures presented in European Worm Meeting. Unpublished information; cite only with author permission.
Gary Williams1, Paul Davis1, Anthony Rogers1, Philip Ozersky2, John Spieth2, Tamberlyn Bieri2, Darin Blasiar2. WormBase is an international consortium of biologists and computer scientists from Caltech (USA), Cold Spring Harbor Laboratory (USA), Wellcome Trust Sanger Institute (UK) and the Genome Sequencing Center at Washington University (USA).. WormBase is dedicated to providing the research community with accurate, current, accessible information concerning the genetics, genomics and biology of C. elegans, and some related nematodes. WormBase can be freely accessed at www.wormbase.org, and is also available for download at ftp://ftp.wormbase.org/pub/wormbase A new data release is produced every three weeks. Recently some new datasets have been added to the database to aid curation.The protein products from automated gene prediction in C. remanei have been mapped to the C. elegans genome; InterPro motifs are no longer taken from SwissProt annotations, but are directly predicted from the C. elegans proteins; contigs of ESTs from other nematode species produced by the NEMBASE and Nematode.net projects have been mapped to the genome and a new set of TEC-REDs have been mapped to the genome resulting in 3,325 new trans-spliced sites which mark the 5'' ends of genes or isoforms. Work is underway to classify and curate transposons and we intend to add Mass-Spec data from several sources to improve coding sequence validation.. Over the last year the curated coding sequences have increased from 19,854 to 20,060 and alternately spliced isoforms have increased from 2,772 to 2,883. The number of genes where every base of every exon is confirmed by EST evidence has increased from 6,427 to 6,584. In the C. elegans proteins there have been 630 modified entries, 440 deleted entries, 709 new entries and 64 reappeared entries.. WormBase is supported by a grant from the National Human Genome Research Institute at the US National Institute of Health #P41 HG02223 and the British Medical Research Council.