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Resources » Paper

Huang P et al. (2005) Cytokine Growth Factor Rev "FGF signaling in flies and worms: more and more relevant to vertebrate biology."

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  • Comments on Huang P et al. (2005) Cytokine Growth Factor Rev "FGF signaling in flies and worms: more and more relevant to vertebrate biology." (0)

  • Overview

    PMID:
    15863031
    DOI:
    10.1016/j.cytogfr.2005.03.002
    Status:
    Publication type:
    Review
    WormBase ID:
    WBPaper00025107

    Huang P, & Stern MJ (2005). FGF signaling in flies and worms: more and more relevant to vertebrate biology. Cytokine Growth Factor Rev, 16, 151-8. doi:10.1016/j.cytogfr.2005.03.002

    FGF signaling in the invertebrate model systems Drosophila melanogaster and Caenorhabditis elegans was initially most obviously involved in cell motility events. More recently, however, FGFs and FGF signaling in these systems have been shown to affect many additional cellular processes. This recent work has shown that the pleiotropies of these FGF receptors resemble those of their vertebrate counterparts, and, in many cases, serve as excellent models for understanding the fundamental molecular mechanisms controlling these events.


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