Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.
  • page settings
  • hide sidebar
  • show empty fields
  • layout
  • (too narrow)
  • open all
  • close all
Resources » Paper

Higashijima S et al. (1992) Genes Dev "Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2."

  • History

  • Referenced

  • Tree Display

  • My Favorites

  • My Library

  • Comments on Higashijima S et al. (1992) Genes Dev "Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2." (0)

  • Overview

    PMID:
    1350558
    DOI:
    10.1101/gad.6.6.1005
    Status:
    Publication type:
    Journal_article
    WormBase ID:
    WBPaper00013305

    Higashijima S, Michiue T, Emori Y, & Saigo K (1992). Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2. Genes Dev, 6, 1005-18. doi:10.1101/gad.6.6.1005

    BarH1 and BarH2 are two closely related homeo box genes that form a small complex at the Bar locus on the X chromosome of Drosophila. By immunostaining, we showed that BarH1 and BarH2 proteins are coexpressed in cells belonging to the central and peripheral nervous systems in embryos. In external sensory (es) organs, their expression was particularly apparent in thecogens (glial cells) and neurons at late development. Although deletion of BarH2 caused no appreciable morphological change in es organs, the simultaneous deletion of BarH1 and BarH2 led to a homeotic change in these organs with consequent conversion from campaniform-like sensilla to trichoid sensilla. In contrast, the overexpression of either BarH1 or BarH2 resulted in opposite morphological change. It would thus follow that BarH1 and BarH2 are a pair of redundant homeo box genes required for the subtype specification of es organs.


    Tip: Seeing your name marked red? Please help us identify you.