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Resources » Paper

Mitchell WA et al. (2001) Eur J Paediatr Neurol "Genomic structure of three CLN3-like genes in Caenorhabditis elegans."

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  • Comments on Mitchell WA et al. (2001) Eur J Paediatr Neurol "Genomic structure of three CLN3-like genes in Caenorhabditis elegans." (0)

  • Overview

    PMID:
    11588982
    DOI:
    10.1053/ejpn.2000.0447
    Status:
    Publication type:
    Journal_article
    WormBase ID:
    WBPaper00004972

    Mitchell WA, Porter M, Kuwabara P, & Mole SE (2001). Genomic structure of three CLN3-like genes in Caenorhabditis elegans. Eur J Paediatr Neurol, 5SA, 121-5. doi:10.1053/ejpn.2000.0447

    The genome of Caenorhabditis elegans is predicted to carry three genes similar to CLN3, the gene underlying juvenile neuronal ceroid lipofuscinosis. All three genes are transcribed and the genomic structure has been determined. The number and position of exons for two of the genes differ from that predicted from the genomic sequence, but no discrepancies with the genomic nucleotide sequence were found. Gene F07B10.1 (cln-3.1) is predicted to have 7 exons and to encode a protein of 424 amino acids. Gene C01G8.2 (cln-3.2) has 9 exons and encodes a protein of 435 amino acids. Gene ZC190.1 (cln-3.3) is predicted to have 9 exons and to encode a protein of 416 amino acids.


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