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Resources » Paper

Schierenberg E (1984) Wissenschaftlechen Filmen, Sekt. Biol. "Embryonic development of the nematode Caenorhabditis elegans."

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    Status:
    Publication type:
    Review
    WormBase ID:
    WBPaper00002088

    Schierenberg E (1984). Embryonic development of the nematode Caenorhabditis elegans. Wissenschaftlechen Filmen, Sekt. Biol..

    Summary of the Film: Embryonic Development of the Nematode Caenorhabditis elegans. A major part of the body cavity of the free-living nematode Caenorhabditis elegans is occupied by oocytes and fertilized eggs. Within about 12 hours the fertilized egg develops into a worm. The transparent eggshell and the ability to develop normal outside the mother allow detailed microscopic observation of cellular development. After fertilization both pronuclei are positioned at opposite poles of the uncleaved egg. They migrate towards each other, fuse and form the zygote. A series of asymmetric divisions results in the formation of 5 "somatic founder cells" and one "primordial germ cell". In addition to the typical synchronous cell divisions within individual cell lines characteristic cell and nuclear migrations during embyrogenesis are shown. Taking the primordial gut cells as an example, formation of an organ is described. Colored computer reconstructions aid a better understanding of cellular topography and document early formation of symmetry within individual cell lines. After the first half of embryonic development nearly all cells are present. During the second half the ball of cells stretch, first muscle contractions occur, gradually a worm is formed. When it hatches, it is about 4x as long as the long axis of the egg shell.


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