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Resources » Paper

Binder BF et al. (1992) Journal of Agricultural and Food Chemistry "Inhibition of Development in Caenorhabditis elegans (Nematoda) by a reduced aromatic schiff base and related compounds."

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  • Comments on Binder BF et al. (1992) Journal of Agricultural and Food Chemistry "Inhibition of Development in Caenorhabditis elegans (Nematoda) by a reduced aromatic schiff base and related compounds." (0)

  • Overview

    DOI:
    10.1021/jf00021a001
    Status:
    Publication type:
    Journal_article
    WormBase ID:
    WBPaper00001613

    Binder BF, Demilo AB, Kochansky JP, & Chitwood DJ (1992). Inhibition of Development in Caenorhabditis elegans (Nematoda) by a reduced aromatic schiff base and related compounds. Journal of Agricultural and Food Chemistry, 40, 1475-1477. doi:10.1021/jf00021a001

    Insect growth regulators with dissimilar chemical structures possess biological activity in parasitic and free-living nematodes. Certain steroids inhibit growth and reproduction in Caenorhabditis elegans, Nippostrongylus brasiliensis, and Heligmosoides polygyrus (=Nematospiroides dubius). Sesquiterpenoid insect juvenile hormones and their analogs disrupt the development of a wide variety of nematodes, whereas nonterpenoid insect juvenile hormone mimics such as benzimidazoles and methoxyphenyl ethers inhibit egg hatch in the pinewood nematode, Bursaphelenchus xylophilus, and reduce growth in a goat parasite, Haemonchus contortus. The insect anti-juvenile hormone precocene II has biological activity against Caenorhabditis remanei, but its role as a nematode antihormone has not been fully clarified. The impact of these compounds on the hormonal systems in insects is fairly clear; their role as endocrine-active bioregulators in nematodes has not yet


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