Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.
  • page settings
  • hide sidebar
  • show empty fields
  • layout
  • (too narrow)
  • open all
  • close all
Resources » Paper

Nelson GA et al. (1992) Int J Rad Appl Instrum D "Radiobiological studies with the nematode Caenorhabditis elegans. Genetic and developmental effects of high LET radiation."

  • History

  • Referenced

  • Tree Display

  • My Favorites

  • My Library

  • Comments on Nelson GA et al. (1992) Int J Rad Appl Instrum D "Radiobiological studies with the nematode Caenorhabditis elegans. Genetic and developmental effects of high LET radiation." (0)

  • Overview

    PMID:
    11537531
    DOI:
    10.1016/1359-0189(92)90102-2
    Status:
    Publication type:
    Journal_article
    WormBase ID:
    WBPaper00001498

    Nelson GA, Schubert WW, & Marshall TM (1992). Radiobiological studies with the nematode Caenorhabditis elegans. Genetic and developmental effects of high LET radiation. Int J Rad Appl Instrum D, 20, 227-32. doi:10.1016/1359-0189(92)90102-2

    The biological effects of heavy charged particle (HZE) radiation are of particular interest to travellers and planners for long-duration space flights where exposure levels represent a potential health hazard. The unique feature of HZE radiation is the structured pattern of its energy deposition in targets. There are many consequences of this feature to biological endpoints when compared with effects of ionizing photons. Dose vs response and dose-rate kinetics may be modified, DNA and cellular repair systems may be altered in their abilities to cope with damage, and the qualitative features of damage may be unique for different ions. The nematode Caenorhabditis elegans is being used to address these and related questions associated with exposure to radiation. HZE-induced mutation, chromosome aberration, cell inactivation and altered organogenesis are discussed along with plans for radiobiological experiments in space.


    Tip: Seeing your name marked red? Please help us identify you.