WBPaper00036464:S.aureus-RN6390_regulated

The two conditions were then compared in Resolver to determine fold change for each probe set and a p-value, using a modified t test. Genes with a 2-fold or greater fold change and a p-value ,0.01 were considered differentially expressed. Genes with altered expression after 8 h S. aureus infection.

WBPaper00036231:long-telomeres_downregulated

t statistics Down-regulated genes in long telomeric worms(HRP-1

WBPaper00036231:long-telomeres_upregulated

t statistics Up-regulated genes in long telomeric worms (HRP-1

WBPaper00035588:alg-1(-)_upregulated

t-statistic difference of > 2.5 with p < 0.01. Genes upregulated by alg-1(-).

WBPaper00062684:pathogen_downregulated_N2

DESeq2 (v.3.1.0), adjusted P-value < 0.05 and fold change >= 2. Transcripts in N2 animals that showed significantly decreased expression across all pathogens (S. epidermidis, P. rettgeri, P. aeruginosa, or S. aureus vs. OP50)

WBPaper00062684:pathogen_upregulated_CB4856

DESeq2 (v.3.1.0), adjusted P-value < 0.05 and fold change >= 2. Transcripts in CB4856 animals that showed significantly increased expression across all pathogens (S. epidermidis, P. rettgeri, P. aeruginosa, or S. aureus vs. OP50)

WBPaper00062684:pathogen_upregulated_N2

DESeq2 (v.3.1.0), adjusted P-value < 0.05 and fold change >= 2. Transcripts in N2 animals that showed significantly increased expression across all pathogens (S. epidermidis, P. rettgeri, P. aeruginosa, or S. aureus vs. OP50)

WBPaper00062684:pathogen_downregulated_CB4856

DESeq2 (v.3.1.0), adjusted P-value < 0.05 and fold change >= 2. Transcripts in CB4856 animals that showed significantly decreased expression across all pathogens (S. epidermidis, P. rettgeri, P. aeruginosa, or S. aureus vs. OP50)

WBPaper00061508:S.aureus_12h_upregulated

N.A. Proteins that showed significantly increased expression after 12 hours of exposure to S. aureus.

WBPaper00040990:PA14_downregulated

Gene expression profiles obtained with microarrays were analyzed by a multi-class t-test using Significance Analysis of Microarrays (SAM), implemented as part of the TMEV software package. Based on T statistics the test retrieves genes with a T value above a cutoff score estimated to give the desired false discovery rate (selected to be 10%). Genes with expression level repressed by bacteria strain PA14.