DR1809

Caenorhabditis elegans

PD4285

Caenorhabditis elegans

Y6B3B.9

Caenorhabditis elegans

Predicted to enable endonuclease activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Human ortholog(s) of this gene implicated in Wilson-Turner syndrome. Is an ortholog of human LAS1L (LAS1 like ribosome biogenesis factor).

eel-1

Caenorhabditis elegans

Predicted to enable ubiquitin protein ligase activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; hemidesmosome assembly; and signal transduction in response to DNA damage. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including hermaphrodite gonad; intestine; neurons; pharynx; and vulva. Used to study syndromic X-linked intellectual disability. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Turner type. Is an ortholog of human HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1).

WBPaper00045417:128Q-huntingtin_upreglated

Authors performed the statistial analysis of the microarray data using the Varmixt tool of the R package, with VM parameters and FDR corrections of P-Values. Genes that showed increased expression in polyQ-expanded hungtingtin (HTT) 128Q touch receptor cells comparing to in 19Q touch receptor cells.

WBPaper00045417:128Q-huntingtin_downreglated

Authors performed the statistial analysis of the microarray data using the Varmixt tool of the R package, with VM parameters and FDR corrections of P-Values. Genes that showed decreased expression in polyQ-expanded hungtingtin (HTT) 128Q touch receptor cells comparing to in 19Q touch receptor cells.

WBPaper00045417:19Q-huntingtin_upreglated

Authors performed the statistial analysis of the microarray data using the Varmixt tool of the R package, with VM parameters and FDR corrections of P-Values. Genes that showed increased expression in normal huntingtin (HTT) expressing 19Q touch receptor cells comparing to in GFP-only touch receptor cells.

WBPaper00045417:19Q-huntingtin_downreglated

Authors performed the statistial analysis of the microarray data using the Varmixt tool of the R package, with VM parameters and FDR corrections of P-Values. Genes that showed decreased expression in normal huntingtin (HTT) expressing 19Q touch receptor cells comparing to in GFP-only touch receptor cells.