- HAL9
Saccharomyces cerevisiae Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression; HAL9 has a paralog, TBS1, that arose from the whole genome duplication
- ENA1
Saccharomyces cerevisiae P-type ATPase sodium pump; involved in Na+ and Li+ efflux to allow salt tolerance
- ENA2
Saccharomyces cerevisiae P-type ATPase sodium pump; involved in Na+ efflux to allow salt tolerance; likely not involved in Li+ efflux
- na-PF
Drosophila melanogaster Flybase gene name is na-PF
- ISC1
Saccharomyces cerevisiae Inositol phosphosphingolipid phospholipase C; hydrolyzes complex sphingolipids to produce ceramide; regulates the spindle assembly checkpoint upstream of PP2A-Cdc55; activates genes required for non-fermentable carbon source metabolism during the diauxic shift; mediates Na+ and Li+ halotolerance; activated by phosphatidylserine, cardiolipin and phosphatidylglycerol; mitochondrial outer membrane protein; ortholog of mammalian neutral sphingomyelinase type 2
- NHERF1
Homo sapiens Na(+)/H(+) exchange regulatory cofactor NHE-RF1
- PDZK1
Homo sapiens Na(+)/H(+) exchange regulatory cofactor NHE-RF3
- NHERF2
Homo sapiens Isoform 1 of Na(+)/H(+) exchange regulatory cofactor NHE-RF2
- PDZD3
Homo sapiens Isoform 3 of Na(+)/H(+) exchange regulatory cofactor NHE-RF4
- NHERF4
Homo sapiens Isoform 1 of Na(+)/H(+) exchange regulatory cofactor NHE-RF4