- FRE3
Saccharomyces cerevisiae Ferric reductase; reduces siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels
- FRE8
Saccharomyces cerevisiae Protein with sequence similarity to iron/copper reductases; involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p
- FTR1
Saccharomyces cerevisiae High affinity iron permease; involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron; protein abundance increases in response to DNA replication stress
- IREB2
Homo sapiens Iron-responsive element-binding protein 2
- FRA1
Saccharomyces cerevisiae Protein involved in negative regulation of iron regulon transcription; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to repress transcription of iron regulon and is defective in spore formation
- AFT2
Saccharomyces cerevisiae Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; AFT2 has a paralog, AFT1, that arose from the whole genome duplication
- FRE4
Saccharomyces cerevisiae Ferric reductase; reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels
- ACP7
Homo sapiens Iron/zinc purple acid phosphatase-like protein
- ISCA1
Homo sapiens Iron-sulfur cluster assembly 1 homolog, mitochondrial
- ISCA2
Homo sapiens Iron-sulfur cluster assembly 2 homolog, mitochondrial