- fu-PA
Drosophila melanogaster Flybase gene name is fu-PA
- Su(fu)-PA
Drosophila melanogaster Flybase gene name is Su(fu)-PA
- LOG1
Saccharomyces cerevisiae Putative protein of unknown function; functions together with HAM1 to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA, without affecting uptake or incorporation of uracil into RNA; proposed to be involved in the metabolism of purine and pyrimidine base analogues; deletion mutants are sensitive to HAP and AHA
- HAM1
Saccharomyces cerevisiae Nucleoside triphosphate pyrophosphohydrolase; active against various substrates including ITP, dITP and XTP; mediates exclusion of non canonical purines, pyrimidines from dNTP pools; functions with YJL055W to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA without affecting uptake or incorporation of uracil into RNA; protein abundance increases in response to DNA replication stress; yeast HAM1 can complement knockdown of human homolog ITPA
- CPD
Homo sapiens Carboxypeptidase D
- CTSD
Homo sapiens Cathepsin D
- CST5
Homo sapiens Cystatin-D
- DDT
Homo sapiens D-dopachrome decarboxylase
- DLD2
Saccharomyces cerevisiae D-2-hydroxyglutarate dehydrogenase, and minor D-lactate dehydrogenase; mitochondrial matrix protein that oxidizes D-2-hydroxyglutarate (D-2HG), an oncometabolite, to alpha-ketoglutarate with a minor role in lactate catabolism; located in the mitochondrial matrix
- DSD1
Saccharomyces cerevisiae D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia by a reaction dependent on pyridoxal 5'-phosphate and zinc; may play a role in D-serine detoxification; L-serine is not a substrate