Picture from Hsu TY et al. (2010) Curr Biol "Engulfment of apoptotic cells in C. elegans is mediated by integrin alpha/SRC ...."

(Ba-Bd) INA-1::GFP and SRC-1::mCherry are colocalized to the pseudopods extending around an apoptotic cell. INA-1::GFP (Ba), SRC-1::mCherry (Bb), merged INA-1::GFP and SRC-1::mCherry (Bc), and DIC (Bd) images of the same embryo coexpressing Pced-1ina-1::gfp and Pced-1src-1::mcherry are shown. Apoptotic cells are indicated by arrows and are magnified in the insets. Scale bar in (Ba) represents 5 um.

Picture from Fletcher M et al. (2017) PLoS Genet "Age-Dependent Neuroendocrine Signaling from Sensory Neurons Modulates the ...."

Fig 5. daf-7 expression declines in aging animals. A) Expression pattern of ksIs2[daf-7p::GFP] reporter in young (i,ii) and aged (iii,iv)animals. Solid triangles indicate ASI neurons, open triangles indicate ASJ neurons. B) Quantification of GFP expression driven by ksIs2[daf-7p::GFP], normalized to exposure time. Representative of 4 replicates with n>10 animals per day. *** represents p < 0.001 by one-way ANOVA C)Quantification of GFP expression driven by cuIs5[C183::myo-2p::GFP] in aging animals, normalized to exposure time. WT statistics indicated ongraph, daf-7(e1372) statistics- Day 3 p = 0.0002; Day 5 p = 0.5225; Day 7 p = 0.0005; Day 9 p = 0.0445; all differences in daf-7(e1372) are aresult of increased GFP fluorescence later in life. Representative of 4 replicates with n>10 animals per genotype per day. *** representsp < 0.001 by one-way ANOVA D) Summary of lifespan experiments initiating BD at various times in adulthood. * indicates BD lifespan wassignificantly different (p < 0.005) than fed control group in all experiments. See S4 Table for individual experiment details

Picture from Kim HS et al. (2014) Genetics "The novel secreted factor MIG-18 acts with MIG-17/ADAMTS to control cell ...."

(A) Wild-type and mig-18(k140) young adults that express MIG-17-Venus.

Picture from Quach TK et al. (2013) PLoS One "Genome-wide microarrray analysis reveals roles for the REF-1 family member ...."

Expression of an integrated transgenic reporter of ftn-1 activity in young adult wild-type animals.

Picture from Hsu TY et al. (2010) Curr Biol "Engulfment of apoptotic cells in C. elegans is mediated by integrin alpha/SRC ...."

Figure 3. SRC-1 Physically Interacts with INA-1(i) and CED-2 In Vitro and Is Colocalized with INA-1 in Phagocytes to the Pseudopods Extending around Apoptotic Cells. (A) SRC-1 interacts with INA-1(i) and CED-2 in the yeast two-hybrid assay. Pairs of constructs expressing the indicated fusion proteins were transformed into the yeast strain MaV203. The resulting transformants were streaked on SC-Trp-Leu-His or SC-Trp-Leu plates containing 25 mM 3AT. Growth on the SC-Trp-Leu-His + 25 mM 3AT plate indicates interaction of fusion proteins.(Ba-Bd) INA-1::GFP and SRC-1::mCherry are colocalized to the pseudopods extending around an apoptotic cell. INA-1::GFP (Ba), SRC-1::mCherry (Bb), merged INA-1::GFP and SRC-1::mCherry (Bc), and DIC (Bd) images of the same embryo coexpressing Pced-1ina-1::gfp and Pced-1src-1::mcherry are shown. Apoptotic cells are indicated by arrows and are magnified in the insets. Scale bar in (Ba) represents 5 um.

Picture from Gruninger TR et al. (2008) PLoS Genet "Sensory perception of food and insulin-like signals influence seizure ...."

(B) Pplc-3:YFP expression pattern in young adult male. The ventral protractors are labeled. Scale bar 6 um.

Picture from Benard C et al. (2001) Development "The C. elegans maternal-effect gene clk-2 is essential for embryonic ...."

Northern and western analyses of clk-2 at all developmental stages (E, embryos; L1-L4, larval stages; A, young adults; glp-4(bn2ts) adults).

Picture from Pispa J et al. (2008) BMC Dev Biol "C. elegans dss-1 is functionally conserved and required for oogenesis and larval ...."

dss-1 mRNA is expressed at different larval ages (L1-L4) and in adult worms (ya, young adult) as shown by RT-PCR. act-4, actin(M03F4.2).

Picture from Carnell L et al. (2005) J Neurosci "The G-protein-coupled serotonin receptor SER-1 regulates egg laying and male ...."

B, C, Expression pattern of Pser-1::gfp in L1 hermaphrodite larvae. Pser-1::gfp(egEx21) contains an 8 kB upstream ser-1 promoter and is expressed in pharyngeal muscle, neurons in the head, ventral cord, and tail of L1 larvae. D, Expression of Pser-1::gfp(egEx21) in young adults. Pser-1::gfp is expressed in the vulval muscles in young adult hermaphrodites.

Picture from Noble LM et al. (2015) Curr Biol "Natural Variation in plep-1 Causes Male-Male Copulatory Behavior in ...."

(A) Maximum intensity projection along the dorsoventral axis showing pplep-1::GFP expression in the excretory cell body, just posterior to the terminal pharyngeal bulb, and symmetric canals in a young adult hermaphrodite. (B) Lateral view of a young adult male. In addition to consistent expression in the excretory cell, fluorescence in two dorsal cells in the male tail, shown here, was observed inconsistently.