Picture from Severson AF et al. (2002) Curr Biol "A Formin Homology protein and a profilin are required for cytokinesis and ...."

(B) PFN-1 is detectable in the cytoplasm and at the cortex of wild-type embryonic cells. Profilin is present at similar levels in the cleavage furrows of dividing cells and elsewhere at the cortex. Cortical and cytoplasmic staining are both reduced in pfn-1(RNAi) embryos. Nonspecific centrosomal staining is sometimes observed in both wild-type and pfn-1(RNAi) embryos.

Picture from Severson AF et al. (2002) Curr Biol "A Formin Homology protein and a profilin are required for cytokinesis and ...."

Figure 2. PFN-1 Is Required for the Cortical Localization of Actin and Myosin (A) Actin and NMY-2 localize around the cortex of wild-type embryos. The levels of both proteins are reduced at the cortex of pfn- 1(RNAi) embryos. (B) PFN-1 is detectable in the cytoplasm and at the cortex of wild-type embryonic cells. Profilin is present at similar levels in the cleavage furrows of dividing cells and elsewhere at the cortex. Cortical and cytoplasmic staining are both reduced in pfn-1(RNAi) embryos. Nonspecific centrosomal staining is sometimes observed in both wild-type and pfn- 1(RNAi) embryos.

Picture from Severson AF et al. (2009) Genes Dev "The axial element protein HTP-3 promotes cohesin loading and meiotic axis ...."

SYP-1 localizes in pachytene nuclei of wild-type animals.

Picture from Severson AF et al. (2009) Genes Dev "The axial element protein HTP-3 promotes cohesin loading and meiotic axis ...."

Figure 8. AE assembly requires HTP-3. (A) HTP-3 and SYP-1 colocalize in pachytene nuclei of wild-type animals. Cruciform HTP-3 staining is observed on diakinesis bivalents. HTP-3 staining persists in htp-1 htp-2 and him-3 mutants. HTP-3 is undetectable in htp-3(y428) animals, and SYP-1 is present in polycomplexes, as previously described in htp-3(RNAi) animals (Goodyer et al. 2008). (A-C) Sister chromatids appear slightly separated in diakinesis univalents of htp-3(y428) and htp-3(RNAi) animals. (B,C) HTP-3 is required for the association of HTP-1/2 and HIM-3 with meiotic chromosomes. HTP-1/2 and HIM-3 colocalize with SYP-1 in pachytene nuclei of wild-type animals. HIM-3 is present along both arms of diakinesis bivalents (C), while HTP-1/2 associate exclusively with the long arm (B). HTP-1/2 and HIM-3 are undetectable on meiotic chromosomes of htp-3(y428) animals. HIM-3 is present in polycomplexes in pachytene nuclei.

Picture from Jedrusik MA et al. (2002) J Cell Sci "A novel linker histone-like protein is associated with cytoplasmic filaments in ...."

Fig. 7. Embryonic expression and subnuclear localization of H1.X. (A,B) show H1.X::GFP fluorescence detection in a few cells in the periphery of a >100-cell stage embryos. In (A), a fixed specimen shows a shallow fluorescence of the nucleoplasm and bright fluorescence of the nucleoli, whereas in (B), a live observation shows a shallow fluorescence in the cytoplasm and a bright fluorescence of the nucleoplasm. The brightest spots in the nucleoplasm correspond to the nucleoli. Bars, 20 μm.

Picture from Chen F et al. (2000) Science "Translocation of C. elegans CED-4 to nuclear membranes during programmed cell ...."

(A) CED-9 expression in a WT embryo of ~30 to 50 cells. (B) Mitotracker Red localization in the same embryo as in (A). (C) Merged image of (A) and (B).

Picture from van Wolfswinkel JC et al. (2009) Cell "CDE-1 affects chromosome segregation through uridylation of CSR-1-bound ...."

ISH of whole mount and extruded gonads with a probe antisense to cde-1. A sense probe was used as a control.

Picture from Zhang S et al. (2004) Curr Biol "MEC-2 is recruited to the putative mechanosensory complex in C. elegans touch ...."

(A) MEC-2 and UNC-24::GFP puncta colocalize in a PLM process.

Picture from Kritikou EA et al. (2006) Genes Dev "C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway ...."

(A) A Northern blot of total RNA isolated from synchronized wild-type animals was probed with a gla-3 cDNA as described in Materials and Methods. Beta-Tubulin was used as a loading control.

Picture from Millonigg S et al. (2014) PLoS Genet "GLD-4-mediated translational activation regulates the size of the ...."

(A) GLD-4 expression is equal across the distal germ line. GLD-2 intensities increase from low-to-high in a distal-to-proximal manner. Extruded gonads of indicated genotype stained with DAPI, a-GLD-2, a-GLD-4, and a-GLH-2 as a positive tissue penetration control (not shown). Asterisk, distal tip; arrowhead, mitosis-to-meiosis boundary.