Figure 1. Neuropeptide conformation impacts behavioral response to ascr#8 detection in male loss of
flp-3 function worms:A) Peptides produced by the
flp-3 gene presented in the current study. B) FLP-3-2 (light blue) and the threonine in position 8 (T8) from the N-terminus (orange) inhibits avoidance, FLP-3-9 (dark blue) and T8 (orange) inhibits avoidance and promoted attraction. C) FLP-3-1 (rose) promoted avoidance while FLP-3-2 (light blue) inhibits avoidance, both contain the first 7 amino acids except for a serine in position 8 for FLP-3-1 (tan). D) FLP-3-7 (magenta) and E8 (tan) promotes avoidance, FLP-3-7T (cyan) and T8 (orange) inhibits avoidance. E) FLP-3-7T superimposed with, FLP-3-1, FLP-3-2, FLP-3-7,and FLP-3-9.