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Picture from Ou, G et al. (2005) Curr Biol "The PKD protein qilin undergoes intraflagellar transport."

Figure 1. The qilin homolog, DYF-3, is an essential component of the IFT machinery that builds sensory cilia. The dyf-3 (m185) mutant has truncated chemosensory cilia and displays no detectable IFT. (A) Wild-type axonemes are 7.5 μm long, containing a 1 μm long basal body, the transition zone, a 4 μm middle segment, and a 2.5 μm distal segment. Arrowheads show the middle-distal segment junctions. Fluorescence micrographs show the distribution of IFT particles (OSM-6::GFP) along the wild-type sensory cilia. (B) The dyf-3 mutant loses its distal segments and has only a truncated middle segment and, moreover, no IFT can be detected in the remaining middle segment. (C) Motility of DYF-3::GFP within sensory cilia. Left panel shows fluorescence micrograph of sensory cilia. Right panels are kymographs with corresponding cartoons showing the lines representing selected DYF-3 particle trajectories along the middle segments (M, M') and the distal segment (D, D'). Kymographs show that motility along the distal segment is faster than along middle segments. Bar = 5 μm.

Picture from Goh KY et al. (2018) Biochim Biophys Acta "A large transcribed enhancer region regulates C. elegans bed-3 and the ...."

(A) bed-3 is expressed in the M lineage including M descendants and SM descendants.

Picture from Robinson-Thiewes, Sarah et al. (2021) MicroPubl Biol

Figure 1. The mpk-1b long first intron enhances MPK-1B translation: (A) The mpk-1 locus generates two RNAs, mpk-1b and mpk-1a; for simplicity, only mpk-1b is shown with its exclusive first exon and 8 kb long first intron. Deletions within the long first intron were generated in the dual tagged (DT) mpk-1 locus, which carries 1XV5 to mark MPK-1B specifically, and 2XOLLAS to mark both MPK-1A and MPK-1B (Robinson-Thiewes et al. 2020a).

Picture from Yang Q et al. (2017) Dev Cell "The Invading Anchor Cell Induces Lateral Membrane Constriction during Vulval ...."

(M-P) Localization of the endogenous GFP::TOCA-1 reporter zh110 in wild-type (M) and unc-6(ev400) mutants (O and P) before (M and O) and after (N and P)lumen formation. (M') and (O') show yz projections of the lateral VulF membranes. The inset in (O) shows the displaced AC in the unc-6(ev400) mutant in a differentfocal plane.

Picture from Hashimshony T et al. (2015) Nature "Spatiotemporal transcriptomics reveals the evolutionary history of the ...."