Picture from Lakdawala, Mohammed Farhan et al. MicroPubl Biol

Figure 1: dpy-2 or dpy-9 loss-of-function mutations affect GFP::DBL-1 and DBL-1 pathway reporter fluorescence in L4 animals. Arrows point to GFP::DBL-1 fluorescent punctae in A and B. Representative images show that loss of dpy-2 or dpy-9 gene function is associated with increased GFP::DBL-1 fluorescence from texIs100 or texIs101 as shown in (A') and (B'), respectively. dpy-2(e8) and dpy-9(e12) mutants also have reduced spp-9p::gfp reporter activity compared to control (C), as shown in (C') and (C''), respectively.