Picture from Bulow HE et al. (2002) Proc Natl Acad Sci U S A "Heparan sulfate proteoglycan-dependent induction of axon branching and axon ...."

Figure 1. The Kallmann syndrome gene kal-1 in C. elegans. (A) Schematic domain structure of the Kallmann syndrome proteins in humans (Hs), worms (Ce), and flies (Dm). Pairwise similarities of domains between proteins were calculated by aligning the domains as predicted by SMART. WAP, whey acidic protein domain; Fn(III), fibronectin III motif; SS, signal sequence. (B) Schematic drawing of the gene structure of C. elegans kal-1 (located on cosmid K03D10) and the transcriptional reporter fusion with green fluorescent protein (gfp) and the unc-54 3' untranslated region. (C) Expression pattern of the kal-1::gfp reporter construct in transgenic animals (otIs33IV).