Picture from Flibotte, Stephane et al. (2021) MicroPubl Biol

Figure 1. Chromosomes I and III in the hT2 balancer: (A) Breakpoint connections deduced by aligning split reads at the breakpoints. Identical strands indicates that the sequence on the left is connected directly to the sequence on the right, while 12/9/2021 - Open Accessdifferent strands denotes a change of strand. Genes affected by the breakpoints are listed in the third column. (B) A schematic representation of chromosomes I and III deduced for hT2 is shown. Each arrow represents the chromosomal segment of the reference sequence with the corresponding coordinates listed. The direction and color of each arrow represent the strand/direction of the sequence within the original reference chromosome. (C) Simplified representation (not at perfect scale) of wild-type (left two chromosomes) and the hT2 translocation (right two chromosomes) with standard marker genes indicated. Chromosome regions in magenta represent segments that are translocated in hT2, while those in black represent untranslocated segments responsible for correct meiotic pairing. For the wild-type chromosomes, the lines at 13.2 Mb (LG I) and 5.0 Mb (LG III) indicate approximate positions of translocation breakpoints from WGS data.