- Picture from Claycomb JM et al. (2009) Cell "The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric ...."
(B) Wild-type perinuclear germline localization of DRH-3,(left, yellow) (DNA, center, blue).(C) DRH-3 (left, green) colocalizes with the P granule component, PGL-1 (center, red; DNA, blue).(D) DRH-3 (left, yellow) remains localized to P granules in the embryonic P cell lineage (dashed circles; DNA, center, blue).
- Picture from Starr DA et al. (2002) Science "Role of ANC-1 in tethering nuclei to the actin cytoskeleton."
(A) Affinity-purified antibodies to ANC-1 were used to probe an immunoblot from a 5% acrylamide gel. Antibodies recognized multiple bands that migrate more slowly than the 175-kD marker. (B and C) ANC-1 antibody localization is pseudocolored red and 4',6'- diamidino-2-phenylindole (DAPI)-stained nuclei are blue. (B) The lateral surface of the mid-body of an L4 N2 worm. ANC-1 antibodies localized to the cytoplasm and were enriched at the nuclear periphery. (C) The extruded gut of an N2 adult.