- excess intestinal cells
Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage.
- head notched
The most anterior portion of the animal contains a V-shaped indentation.
- E lineage variant
The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals.
- V lineages variant
The descendants of any of the V precursor cells (V1-V6) exhibit altered developmental programs compared to their counterparts in control animals.
- no Intestine
Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells.
- male V lineages variant
The descendants of any of the V precursor cells (V1-V6) in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals.
- population fitness phenotype
Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations. In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed.