Y lineage variant

The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.

M lineage variant

The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage.

cell cycle arrest

Cells of the animals cease during one of its replicative phases (G1, S, G2, M).

early exit cell cycle

Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells.

biofilm absent head

Animals can move thorough a lawn of bacterially produced biofilm without accumulating an enormous amount of biofilm on its nose. When C. elegans is exposed to certain bacteria (e.g., Y. pestis), a biofilm accumulates on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth.

male M lineage variant

The descendants of the M precursor cell in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals.

transdifferentiation defective

The conversion of one differentiated cell type into another does not occur as it does in control animals. In C. elegans, the Y cell undergoes a dramatic redifferentiation from being a cell in of the rectum to a PDA neuron. This transdifferentiation requires the cell to withdraw from its established position, migrate, and then become a motor neuron.

G2 checkpoint variant

Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G2 phase of the mitotic cell cycle just before entry into M phase, nuclear division, compared to control cells.

hermaphrodite sex muscle morphology variant

Any variation in the form, structure or composition of the muscles of the adult hermaphrodite reproductive system compared to control. In C. elegans hermaphrodites these muscles include the vulval and uterine muscles, located near the vulva in the midbody, which all derive from the M myoblast (Wormatlas).

male sex muscle morphology variant

Any variation in the form, structure or composition of the muscles of the adult male reproductive system compared to control. In C. elegans males, the M myoblast gives rise to a much larger set of specialized muscles, compared to hermaphrodites, which differentiate within the tail region (Wormatlas).