- excess intestinal cells
Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage.
- no Intestine
Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells.
- E lineage variant
The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals.
- population fitness phenotype
Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations. In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed.
- plugged excretory pore
Males receive copulatory plugs from other males, deposited on their excretory pores. This phenotype is polymorphic among C. elegans strains and also in C. briggsae.
- sodium acetate chemotaxis defective
Failure in directed movement in response to sodium acetate. In C. elegans, sodium acetate is an attractant. Sodium acetate has also subsequently been used to assay for Na+ attraction in C. elegans.
- ammonium chloride chemotaxis defective
Failure in directed movement in response to ammonium chloride compared to control. In C. elegans, NH4Cl is an attractant. NH4Cl has also subsequently been used to assay for Cl- attraction in C. elegans.
- embryonic lethal
Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
- temperature induced dauer formation variant
Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C.