- Q lineage variant
The descendants of Q L or QR cells exhibit altered developmental programs compared to their counterparts in control animals.
- excess intestinal cells
Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage.
- E lineage variant
The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals.
- coenzyme Q depleted
Animals contain a lower level of coenzyme Q, an oil-soluble vitamin-like substance present in most eukaryotic cells, primarily in the mitochondria, compared to control. It is a component of the electron transport chain and participates in aerobic cellular respiration.
- no Intestine
Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells.
- population fitness phenotype
Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations. In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed.