Y lineage variant

The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.

protrusion at vulval region

Large protrusion at the normal position of the vulva, as seen in C. elegans lin-12 null animals.

biofilm absent head

Animals can move thorough a lawn of bacterially produced biofilm without accumulating an enormous amount of biofilm on its nose. When C. elegans is exposed to certain bacteria (e.g., Y. pestis), a biofilm accumulates on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth.

transdifferentiation defective

The conversion of one differentiated cell type into another does not occur as it does in control animals. In C. elegans, the Y cell undergoes a dramatic redifferentiation from being a cell in of the rectum to a PDA neuron. This transdifferentiation requires the cell to withdraw from its established position, migrate, and then become a motor neuron.

EGF-induced sleep variant

Animals do not respond with sleeping behavior induced through the EGF pathway. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals.

EGF-induced sleep resistant

Animals respond with sleeping behavior induced through the EGF pathway, more rigorously than control animals. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals.