McPhee CK et al. (2010) Cell "Autophagy shows its animal side."

McPhee CK, Baehrecke EH

[Cell, 2010]

Most autophagy genes have been discovered in the single-celled yeast Saccharomyces cerevisiae, and little is known about autophagy genes that are specific to multicellular animals. In this issue, Tian et al. (2010) now identify four new autophagy genes: one specific to the nematode Caenorhabditis elegans and three conserved from worms to mammals.