Imanikia S et al. (2020) Dev Cell "Molty-Level Regulation: Lysosomes Participate in Developmental ECM Remodeling in C.elegans."

Taylor RC, Imanikia S

[Dev Cell, 2020]

Dynamic regulation of lysosomes allows them to play key roles in cell and tissue homeostasis. In this issue of Developmental Cell, Miao etal. find that a novel transcriptional pathway triggered by loss of cell adhesion activates lysosomes in C.elegans epidermis during developmental remodeling of the cuticle.