Melander RJ et al. (2015) Chem Biol "From worms to targeting virulence factors."

Melander C, Melander RJ

[Chem Biol, 2015]

Rising antibiotic resistance means that alternative antibacterial strategies are sorely needed. In this issue, Zhu etal. (2015) report the use of a Caenorhabditis elegans model to validate the Pseudomonas aeruginosa virulence factor LasB as a potential therapeutic target and to identify a LasB inhibitor with invivo efficacy.