[
Genetics,
2019]
The Genetics Society of America's (GSA) Thomas Hunt Morgan Medal honors researchers for lifetime achievement in genetics. The recipient of the 2018 Morgan Medal, Barbara J. Meyer of the Howard Hughes Medical Institute and the University of California, Berkeley, is recognized for her career-long, groundbreaking investigations of how chromosome behaviors are controlled. Meyer's work has revealed mechanisms of sex determination and dosage compensation in <i>Caenorhabditis elegans</i> that continue to serve as the foundation of diverse areas of study on chromosome structure and function today, nearly 40 years after she began her work on the topic.
[
Genetics,
1996]
I fell in love with Caenorhabditis elegans in the summer of '72. Our relationship was cemented four years later, 20 years ago now, by the publication of a paper in Genetics on C. elegans chromosome rearrangements (Herman et al. 1976). My pleasant assignment here is to describe the beginning of that work and to relate it to current worm cytogenetics and chromosome mechanics.
[
Science,
2002]
The nematode worm known as Caenorhabditis elegans is not much to look at. Just a millimeter long and transparent to boot, it is almost invisible to the naked eye. But in biological research the tiny worm looms large, providing a model system for studying everything from embryonic development to aging. Now, three researchers who pioneered the use of C. elegans as a model organism have won the Nobel Prize in Physiology or Medicine.
[
Genetics,
2002]
This article marks the 25th anniversary of a paper reporting the first sex-determination mutants to be found in the nematode Caenorhabditis elegans. The isolation of these mutants initiated an extensive analysis of nematode sex determination and dosage compensation, carried out by a number of laboratories over the subsequent decades. As a result, the process of sex determination is now one of the most thoroughly understood parts of C. elegans development, in both genetic and molecular terms. It has also proved to have interesting repercussions on the study of sex determination in other organisms.