Bargmann C (2024) Neuron "Cori Bargmann."

Bargmann C

[Neuron, 2024]

In an interview with Neuron, Cori Bargmann discusses C. elegans as a model organism, the importance of considering the animal's own world (thinking like a worm), choosing a scientific problem, and her experience as head of science at the Chan Zuckerberg Initiative and co-chair of the BRAIN Initiative.

Troemel E (2018) BMC Biol "Host-parasite interactions: an interview with Emily Troemel."

Troemel E

[BMC Biol, 2018]

Emily Troemel is a Professor at the University of California San Diego, where her lab uses Caenorhabditis elegans to study host-pathogen interactions and the shaping of the immune response. In this interview, Emily shared her thoughts on peer review and its role in training future scientists, and the possibility of a new form of immunity in epithelia.

Hodgkin J (2004) Curr Biol "Jonathan Hodgkin."

Hodgkin J

[Curr Biol, 2004]

Jonathan Hodgkin graduated from Oxford in 1971 and then did a PhD with Sydney Brenner at MRC LMB in Cambridge, studying behavioural genetics in the nematode Caenorhabditis elegans. Later, after a couple of years working with myxobacteria as a postdoc in Dale Kaiser''s lab at Stanford, he returned to LMB as a staff member, where he remained for most of the subsequent two decades. In the year 2000, he moved to Oxford as Professor of Genetics in the Department of Biochemistry, switching his major research interests from developmental genetics and sex determination to the study of host-pathogen interactions in the worm. For the past ten years, he has acted as curator of the C. elegans genetic map and gene nomenclature, and he is currently President of the Genetics Society of Great Britain.

Ausubel FM (2014) Genetics "Twists and turns: my career path and concerns about the future."

Ausubel FM

[Genetics, 2014]

THE Genetics Society of America's Thomas Hunt Morgan Medal is awarded to an individual GSA member for lifetime achievement in the field of genetics. The 2014 recipient is Frederick Ausubel, whose 40-year career has centered on host-microbe interactions and host innate immunity. He is widely recognized as a key scientist responsible for establishing the modern postrecombinant DNA field of host-microbe interactions using simple nonvertebrate hosts. He has used genetic approaches to conduct pioneering work that spawned six related areas of research: the evolution and regulation of Rhizobium genes involved in symbiotic nitrogen fixation; the regulation of Rhizobium genes by two-component regulatory systems involving histidine kinases; the establishment of Arabidopsis thaliana as a worldwide model system; the identification of a large family of plant disease resistance genes; the identification of so-called multi-host bacterial pathogens; and the demonstration that Caenorhabditis elegans has an evolutionarily conserved innate immune system that shares features of both plant and mammalian immunity.

Mango S (2009) Curr Biol "Q&A: Susan Mango."

Mango S

[Curr Biol, 2009]

Susan Mango is Benning Professor of Oncological Sciences at the University of Utah and an Investigator at the Huntsman Cancer Institute. She grew up in England and Washington D.C. before attending Harvard University. She received her Ph.D. from Princeton, where she studied the c-myc oncogene with Michael Cole. She was introduced to the nematode Caenorhabditis elegans as a postdoc with Judith Kimble at the University of Wisconsin - Madison, and moved to Utah in 1996 to start her own lab. After 13 years at the University of Utah, she will move to Harvard University in July 2009. Her principal focus is transcriptional strategies of organ development, using the C. elegans foregut as a model.

Weinkove D (2018) BMC Biol "On microbes, aging and the worm: an interview with David Weinkove."

Weinkove D

[BMC Biol, 2018]

David Weinkove is an associate professor at Durham University, UK, studying host-microbe interactions in the model organism Caenorhabditis elegans. David has been focusing on the way microbes affect the physiology of their hosts, including the process of aging. In this interview, he discusses the questions shaping his research, how they evolved over the years, and his guiding principles for leading a lab.

(2024) Development "The people behind the papers - Alyshia Scholl, Yihong Liu and Geraldine Seydoux."

[Development, 2024]

Germ granules have been hypothesized to deliver mRNAs of germ cell fate determinants to primordial germ cells. Now, a new study in Development finds that many mRNAs enriched in germ granules are not involved in germline development in Caenorhabditis elegans. To find out more about the story behind the paper, we caught up with first author Alyshia Scholl, second author Yihong Liu and corresponding author Geraldine Seydoux, Professor at Johns Hopkins University School of Medicine.

(2024) Development "The people behind the papers - Denis Faerberg and Ilya Ruvinsky."

[Development, 2024]

Male pheromones accelerate the development of hermaphrodite larvae in Caenorhabditis elegans, but the importance of this phenomenon is not well understood. A new paper in Development shows that pheromone exposure during larval stage 3 helps coordinate behaviour and development by modulating the timing of the transition to larval stage 4. To learn more about the story behind the paper, we caught up with first author Denis Faerberg who carried out the work in the lab of the corresponding author Ilya Ruvinsky at Northwestern University, USA.