[
Bioinformatics,
2009]
VANO is a cross-platform image annotation system that enables one to conveniently visualize and annotate 3D volume objects including nuclei and cells. An application of VANO typically starts with an initial collection of objects produced by a segmentation computation. The objects can then be labeled, categorized, deleted, added, split, merged, and redefined. VANO has been used to build high-resolution digital atlases of the nuclei of C. elegans at the L1 stage and the nuclei of D. melanogaster''s ventral nerve cord at the late embryonic stage. AVAILABILITY: Platform independent executables of VANO, a sample dataset, and a detailed description of both its design and usage are available at: research.janelia.org/peng/proj/vano. VANO is open-source for co-development.