Tavernarakis N et al. (2001) Curr Biol "Structural and functional features of the intracellular amino terminus of DEG/ENaC ion channels."

Everett JK, Driscoll M, Tavernarakis N, Kyrpides NC

[Curr Biol, 2001]

The degenerin/epithelial sodium channel (DEG/ ENaC) protein family includes related ion channel subunits from organisms ranging from the simple nematode Caenorhabditis elegans to humans. Members of this protein family have been implicated in functions as diverse as touch transduction and proprioception [1-4], pain sensation and maintenance of sodium balance [5].

Sims Iii RJ et al. (2009) Nat Genet "Processing the H3K36me3 signature."

Reinberg D, Sims Iii RJ

[Nat Genet, 2009]

The global patterning of histone lysine methylation has been scrutinized over the years in an effort to uncover unique features indicative of chromatin function. A study in Caenorhabditis elegans now shows that nucleosomes covering exons and introns on active genes are differentially marked by H3K36 trimethylation, suggesting a new mode of communication between chromatin and pre-mRNA processing.