Cadet P et al. (1973) Nematologica "Production of Caenorhabditis elegans mutants under the influence of ethyl-methane-sulfonate (E.M.S.)."

Cadet P, Dion M

[Nematologica, 1973]

Genetic studies of two spontaneous dwarf mutants (n(a) and n(b)) have led Dion and Brun to mark, in C. elegans genome, two of the five autosomes. The use of natural mutants for genetic mapping is, however, unsatisfactory in that they are rare, certainly because of the self-fertilizing reproduction of this free-living nematode; furthermore, most of them appear to be of the n(a) type described by the authors. For these reasons, chemical mutagens have been used, the most efficient being E.M.S.