Gbewonyo K et al. (1997) Biotechnol Genet Eng Rev "Bioreactor cultivation of the nematode Caenorhabditis elegans: large scale production of biologically active drug receptors for pharmaceutical research."

Rohrer SP, Gbewonyo K, Buckland BC

[Biotechnol Genet Eng Rev, 1997]

There is growing interest within the biotechnology community in the study of nematodes, particularly the free-living nematode Caenorhabditis elegans. The fascination of scientists with C. elegans for both basic and applied research is due to the convergence of a number of current trends in modern biology. The selection of the free-living nematode C. elegans as a model organism for elucidating the genetics and developmental biology of multicellular organisms has led to an explosion in biochemical knowledge about C. elegans. The hallmarks of the concerted research efforts on C. elegans over the last 3 decades are summarized in Table 1.