Wood AJ et al. (2015) Dev Cell "A TAD Closer to Understanding Dosage Compensation."

Wood AJ, Bickmore WA

[Dev Cell, 2015]

Eukaryotic chromosomes are organized into topological domains, but how these are established and maintained is poorly understood. Writing in Nature, Crane et al. (2015) show that a specialized condensin complex enforces the domain boundaries along the C. elegans X chromosome to equalize transcription from the X between males and hermaphrodites.