Methyllycaconitine had no effect on wild-type or deg-3 mutants. We do not know whether this lack of effect was due to the absence of a putative binding site (Ward et al., 1990) in DEG-3 or lack of entry into the worms.
These animals showed no hlh-8::gfp expression throughout the M lineage and lacked all M-derived CCs. This is an enhancement of the defects in the M-lineage compared to either RNAi or mutant alone.
These animals showed no hlh-8::gfp expression throughout the M lineage and lacked all M-derived CCs. This is an enhancement of the defects in the M-lineage compared to either RNAi or mutant alone.