nhr-38 : sur-2

"In the suppressor screen, we utilized pleiotropic defects of cmk-1 mutants: cmk-1 mutants showed abnormally low expression of nhr-38 promoter-fused GFP, an AFD neuron-specific GFP marker (Satterlee et al., 2004). Therefore, we mutagenized cmk-1 mutants carrying nhr-38 promoter-fused GFP and found that a mutation in sur-2 gene that encodes the ortholog of human MED23, a subunit of transcription mediator complex (Singh and Han, 1995), restored the expression of the GFP marker in a cmk-1 mutant background (Figures S3A and S3B)."

cmk-1 : sur-2

"In the suppressor screen, we utilized pleiotropic defects of cmk-1 mutants: cmk-1 mutants showed abnormally low expression of nhr-38 promoter-fused GFP, an AFD neuron-specific GFP marker (Satterlee et al., 2004). Therefore, we mutagenized cmk-1 mutants carrying nhr-38 promoter-fused GFP and found that a mutation in sur-2 gene that encodes the ortholog of human MED23, a subunit of transcription mediator complex (Singh and Han, 1995), restored the expression of the GFP marker in a cmk-1 mutant background (Figures S3A and S3B)."